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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NR2C1
All Species:
8.48
Human Site:
T222
Identified Species:
15.56
UniProt:
P13056
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13056
NP_001027458.1
603
67315
T222
S
P
L
T
A
T
P
T
F
V
T
D
S
E
S
Chimpanzee
Pan troglodytes
XP_001137621
678
75113
T297
S
P
L
T
A
T
P
T
F
V
A
D
S
E
S
Rhesus Macaque
Macaca mulatta
XP_001107297
554
61731
M179
Q
R
C
I
A
F
G
M
K
Q
D
S
V
Q
C
Dog
Lupus familis
XP_854792
605
67422
T223
S
P
L
A
A
T
P
T
F
V
T
D
S
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q505F1
590
65487
D214
A
T
P
T
F
V
T
D
S
E
T
A
R
S
A
Rat
Rattus norvegicus
Q8VIJ4
590
65509
D214
A
T
P
T
F
V
T
D
S
E
T
A
R
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510105
561
61971
A186
F
V
T
D
S
E
T
A
R
S
T
G
L
L
D
Chicken
Gallus gallus
O42101
501
57084
N126
D
R
M
R
G
G
R
N
K
F
G
P
M
Y
K
Frog
Xenopus laevis
Q66J63
637
70793
L256
R
K
D
L
R
S
P
L
A
A
T
T
T
F
V
Zebra Danio
Brachydanio rerio
Q06725
411
45463
A36
P
A
R
E
Q
Q
Q
A
A
S
A
A
P
H
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16375
543
57969
G168
S
I
K
G
Q
P
T
G
C
G
S
T
T
P
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N4B8
615
68010
M215
R
L
R
K
C
L
S
M
G
M
R
S
E
S
V
Sea Urchin
Strong. purpuratus
Q26622
583
63834
D207
G
S
V
L
A
G
G
D
M
K
S
P
Q
G
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
90.3
96
N.A.
87.5
87.5
N.A.
77.7
21.5
72.6
27
N.A.
22
N.A.
22.9
49
Protein Similarity:
100
87.6
91.2
97.6
N.A.
92.2
91.7
N.A.
84.7
40.9
82.7
42.7
N.A.
37.8
N.A.
42.1
65.1
P-Site Identity:
100
93.3
6.6
86.6
N.A.
13.3
13.3
N.A.
6.6
0
13.3
0
N.A.
13.3
N.A.
0
6.6
P-Site Similarity:
100
93.3
13.3
93.3
N.A.
26.6
26.6
N.A.
13.3
6.6
26.6
6.6
N.A.
26.6
N.A.
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
0
8
39
0
0
16
16
8
16
24
0
0
8
% A
% Cys:
0
0
8
0
8
0
0
0
8
0
0
0
0
0
8
% C
% Asp:
8
0
8
8
0
0
0
24
0
0
8
24
0
0
8
% D
% Glu:
0
0
0
8
0
8
0
0
0
16
0
0
8
24
0
% E
% Phe:
8
0
0
0
16
8
0
0
24
8
0
0
0
8
0
% F
% Gly:
8
0
0
8
8
16
16
8
8
8
8
8
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
8
8
0
0
0
0
16
8
0
0
0
0
8
% K
% Leu:
0
8
24
16
0
8
0
8
0
0
0
0
8
8
0
% L
% Met:
0
0
8
0
0
0
0
16
8
8
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% N
% Pro:
8
24
16
0
0
8
31
0
0
0
0
16
8
8
0
% P
% Gln:
8
0
0
0
16
8
8
0
0
8
0
0
8
8
0
% Q
% Arg:
16
16
16
8
8
0
8
0
8
0
8
0
16
0
0
% R
% Ser:
31
8
0
0
8
8
8
0
16
16
16
16
24
24
24
% S
% Thr:
0
16
8
31
0
24
31
24
0
0
47
16
16
0
24
% T
% Val:
0
8
8
0
0
16
0
0
0
24
0
0
8
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _